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OncoMatch/Clinical Trials/NCT05769660

A Study to Evaluate Safety and Efficacy of BEY1107 in Combination with Temozolomide in Patients with Recurrent or Progressive Glioblastoma Multiforme (GBM)

Is NCT05769660 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies multiple treatments including BEY1107 and Temozolomide for glioblastoma multiforme.

Phase 1RecruitingBeyondBio Inc.NCT05769660Data as of May 2026

Treatment: BEY1107 · TemozolomideThis is a Phase 1 study to evaluate the maximum tolerated dose, safety and efficacy of BEY1107 in combination with Temozolomide in Patients with Recurrent or Progressive Glioblastoma Multiforme (GBM)

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Extracted eligibility criteria

Cancer type

Glioblastoma

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: chemotherapy

Lab requirements

Blood counts

Patients with inadequate bone marrow function [excluded]

Kidney function

Patients with inadequate kidney function [excluded]

Liver function

Patients with inadequate liver function [excluded]

Patients with inadequate bone marrow, kidney and liver function [excluded]

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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