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OncoMatch/Clinical Trials/NCT05758688

PROton Therapy for Post Surgical Treatment of GYNecologic Cancer

Is NCT05758688 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies non-drug interventions for cervical cancer.

Phase 2RecruitingAbramson Cancer Center at Penn MedicineNCT05758688Data as of Jun 2026

This is a single institution, multi-center, Phase II, single-arm study, using Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) in the post-surgical, adjuvant setting for definitive treatment of gynecologic cancers. The purpose of this study is to estimate rate of acute clinician-reported gastrointestinal (GI) toxicity using WP PBS PRT in the definitive treatment of gynecologic cancers in the post-surgical, adjuvant setting.

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Extracted eligibility criteria

Cancer type

Cervical Cancer

Endometrial Cancer

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Demographics

Female only

Prior therapy

Cannot have received: pelvic radiation

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Virtua Health · Voorhees Township, New Jersey
  • Lancaster General Health - Ann B. Barshinger Cancer Institute · Lancaster, Pennsylvania
  • University of Pennsylvania · Philadelphia, Pennsylvania

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT05758688 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior pelvic radiation disqualifies patients from enrollment.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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