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OncoMatch/Clinical Trials/NCT05754749

Comparison of CE-DBT and MRI in Patients With Known Breast Lesions

Is NCT05754749 recruiting? Yes, currently enrolling (Jun 2026). This Early Phase 1 trial studies Iohexol 350 Mg/mL Injectable Solution for breast cancer.

Early Phase 1RecruitingUNC Lineberger Comprehensive Cancer CenterNCT05754749Data as of Jun 2026

Treatment: Iohexol 350 Mg/mL Injectable SolutionThe purpose of this pilot study is to compare radiologist confidence level in evaluating patients with known breast lesions between contrast enhanced digital breast tomosynthesis (CE- DBT) and contrast enhanced dynamic magnetic resonance imaging (CE-MRI) acquired as a part of a standard clinical workup.

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Extracted eligibility criteria

Treatments studied

Other

Iohexol 350 Mg/mL Injectable Solution

Cancer type

Breast Carcinoma

Demographics

Female only

Lab requirements

Kidney function

serum creatinine level > 1.8 mg/dl or a glomerular filtration rate < 60 as approximated using serum creatinine levels within the last 30 days prior to the research scan unless anuric and on dialysis

Impaired kidney function (serum creatinine level > 1.8 mg/dl or a glomerular filtration rate < 60 as approximated using serum creatinine levels within the last 30 days prior to the research scan) unless anuric and on dialysis

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of North Carolina at Chapel Hill · Chapel Hill, North Carolina

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Frequently asked questions

Is NCT05754749 currently recruiting?

Yes, this trial is currently recruiting patients.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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