OncoMatch

OncoMatch/Clinical Trials/NCT05753618

Evaluating Omission of Granulocyte Colony-stimulating Factors in Breast Cancer Patients Receiving Paclitaxel Portion of Dose-dense Adriamycin-cyclophosphamide and Paclitaxel Chemotherapy

Is NCT05753618 recruiting? Yes, currently enrolling (Jun 2026). This Phase 4 trial studies multiple treatments including Granulocyte Colony-Stimulating Factor (G-CSF) and Omission of Granulocyte Colony-Stimulating Factor (G-CSF) for early-stage breast cancer.

Phase 4RecruitingOttawa Hospital Research InstituteNCT05753618Data as of Jun 2026Location: Canada

Treatment: Granulocyte Colony-Stimulating Factor (G-CSF) · Omission of Granulocyte Colony-Stimulating Factor (G-CSF)The goal of this randomized, pragmatic clinical trial is to evaluate the omission of granulocyte colony-stimulating factors (G-CSF) in breast cancer patients receiving paclitaxel portion of dose-dense adriamycin-cyclophosphamide and paclitaxel (DD-AC/T) chemotherapy. Participants will be randomized to either take G-CSF while on the paclitaxel portion of DD-AC/T chemotherapy or to omit G-CSF while on the paclitaxel portion of DD-AC/T chemotherapy.

Check if I qualify

Extracted eligibility criteria

Treatments studied

Other

Granulocyte Colony-Stimulating Factor (G-CSF)Omission of Granulocyte Colony-Stimulating Factor (G-CSF)

Cancer type

Breast Carcinoma

Disease stage

Excluded: Stage IV

early-stage or locally-advanced breast cancer; Metastatic cancer [excluded]

Prior therapy

Cannot have received: cytotoxic chemotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT05753618 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior cytotoxic chemotherapy disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

Check if I qualify