OncoMatch

OncoMatch/Clinical Trials/NCT05751343

Atezolizumab and Bevacizumab Plus TACE-HAIC for Unresectable Advanced HCC: a Phase 2 Clinical Trial

Is NCT05751343 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies TACE-HACI, plus atezolizumab-bevacizumab for hepatocellular carcinoma.

Phase 2RecruitingSun Yat-sen UniversityNCT05751343Data as of Jun 2026Location: China

Treatment: TACE-HACI, plus atezolizumab-bevacizumabAtezolizumab and bevacizumab was approve for advanced unresectable hepatocellular carcinoma (aHCC). Whether the additional of transartial chemobolization and hepatic artery infusion chemotherapy will improve the response rate for those patients is still unknown. This phase 2 clinical trial aims to investigate the objective response rate for unresectable advanced hepatocellular carcinoma.

Check if I qualify

Extracted eligibility criteria

Treatments studied

Immunotherapy

TACE-HACI, plus atezolizumab-bevacizumab

Cancer type

Hepatocellular Carcinoma

Disease stage

Required: Stage ADVANCED-STAGE

unresectable advanced-stage HCC

Performance status

ECOG 0–1(Restricted strenuous activity)

Demographics

Ages ≤ 75

Lab requirements

Blood counts

white blood cell count >3×10^9/L, absolute neutrophil count >1.5×10^9/L, platelet count >10×10^9/L, hemoglobin concentration >85 g/L

Liver function

Child-Pugh A or B liver function

Child-Pugh A or B liver function; adequate hematologic blood counts (white blood cell count >3×10^9/L, absolute neutrophil count >1.5×10^9/L, platelet count >10×10^9/L, hemoglobin concentration >85 g/L)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT05751343 currently recruiting?

Yes, this trial is currently recruiting patients.

What disease stage is eligible?

Stage ADVANCED-STAGE is required.

Is there an age limit?

Yes. Patients must be 75 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

Check if I qualify