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OncoMatch/Clinical Trials/NCT05704621

Secondary Cytoreductive Surgery (CRS) in Patients With Relapsed Ovarian Cancer Who Have Progressed on PARP Inhibitor Maintenance

Is NCT05704621 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies chemotherapy for ovarian cancer.

Phase 2RecruitingKorea University Guro HospitalNCT05704621Data as of Jun 2026Location: South Korea

Treatment: chemotherapyThis is a randomized phase II study of secondary cytoreductive surgery (CRS) in patients with relapsed ovarian cancer who have progressed on PARP inhibitor maintenance.

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Extracted eligibility criteria

Treatments studied

Other

chemotherapy

Cancer type

Ovarian Cancer

Demographics

Female only

Prior therapy

Max 1 prior line
Min 1 prior line

Must have received: platinum-based chemotherapy

platinum sensitive, invasive epithelial ovarian-, fallopian tube- or primary peritoneal cancer; Progression-free interval of at least 6 months after end of last platinum- containing therapy

Must have received: PARP inhibitor — maintenance

Progressed during PARP inhibitor maintenance

Cannot have received: chemotherapy

Exception: one prior chemotherapy allowed

More than one prior chemotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT05704621 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior chemotherapy disqualifies patients from enrollment.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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