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OncoMatch/Clinical Trials/NCT05694312

Ibrutinib for the Treatment of AIHA in Patients With CLL/SLL or CLL-like MBL

Is NCT05694312 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Ibrutinib 420 mg for autoimmune hemolytic anemia.

Phase 2RecruitingGruppo Italiano Malattie EMatologiche dell'AdultoNCT05694312Data as of May 2026

Treatment: Ibrutinib 420 mgThis is a multicenter, single arm, phase II study aimed at evaluating ibrutinib therapy for the treatment of AIHA in patients with CLL/SLL or CLL-like MBL.

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Extracted eligibility criteria

Cancer type

Chronic Lymphocytic Leukemia

Non-Hodgkin Lymphoma

Prior therapy

Must have received: corticosteroid — AIHA

relapsed after previous treatment with corticosteroids (with or without rituximab), or ... steroid-resistant ... or ... steroid-dependent

Cannot have received: BTK inhibitor (ibrutinib)

Previous exposure to ibrutinib as CLL-directed therapy.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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