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OncoMatch/Clinical Trials/NCT05694312

Ibrutinib for the Treatment of AIHA in Patients With CLL/SLL or CLL-like MBL

Is NCT05694312 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Ibrutinib 420 mg for autoimmune hemolytic anemia.

Phase 2RecruitingGruppo Italiano Malattie EMatologiche dell'AdultoNCT05694312Data as of Jun 2026Location: Italy

Treatment: Ibrutinib 420 mgThis is a multicenter, single arm, phase II study aimed at evaluating ibrutinib therapy for the treatment of AIHA in patients with CLL/SLL or CLL-like MBL.

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Extracted eligibility criteria

Treatments studied

Other

Ibrutinib 420 mg

Cancer type

Chronic Lymphocytic Leukemia

Prior therapy

Must have received: corticosteroid — AIHA

relapsed after previous treatment with corticosteroids (with or without rituximab), or ... steroid-resistant ... or ... steroid-dependent

Cannot have received: BTK inhibitor (ibrutinib)

Previous exposure to ibrutinib as CLL-directed therapy.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT05694312 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior BTK inhibitor disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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