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OncoMatch/Clinical Trials/NCT05692024

COffee and Metabolites Modulating the Gut MicrobiomE in Colorectal caNCER

Is NCT05692024 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies Nestlé NESCAFÉ® TASTER'S CHOICE® House Blend capsule. for colorectal cancer.

Phase 1/2RecruitingMassachusetts General HospitalNCT05692024Data as of May 2026

Treatment: Nestlé NESCAFÉ® TASTER'S CHOICE® House Blend capsule.This is research study is assessing the effects of 6-g daily use of freeze-dried instant coffee on liver fat and fibrosis and the gut microbiome and metabolome in patients who have completed routine treatment (including surgery, chemotherapy and radiotherapy) for stage I-III colorectal cancer.

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Extracted eligibility criteria

Cancer type

Colorectal Cancer

Disease stage

Required: Stage I, II, III

Prior therapy

Must have received: surgery — standard treatment

have completed standard treatment (including surgery, chemotherapy and radiotherapy) at least 2 months ago

Must have received: chemotherapy — standard treatment

have completed standard treatment (including surgery, chemotherapy and radiotherapy) at least 2 months ago

Must have received: radiation therapy — standard treatment

have completed standard treatment (including surgery, chemotherapy and radiotherapy) at least 2 months ago

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Massachusetts General Hospital · Boston, Massachusetts

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