OncoMatch

OncoMatch/Clinical Trials/NCT05675787

Medroxyprogesterone Acetate Plus Atorvastatin in Young Women With Early Endometrial Carcinoma and Atypical Endometrial Hyperplasia

Is NCT05675787 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Medroxyprogesterone acetate + Atorvastatin for atypical endometrial hyperplasia.

Phase 2RecruitingPeking University People's HospitalNCT05675787Data as of Jun 2026Location: China

Treatment: Medroxyprogesterone acetate + AtorvastatinTo explore the treatment efficacy of medroxyprogesterone acetate plus atorvastatin in patients with atypical endometrial hyperplasia (AEH) and early endometrial carcinoma (EEC) for conservative treatment.

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Extracted eligibility criteria

Treatments studied

Other

Medroxyprogesterone acetate + Atorvastatin

Cancer type

Endometrial Cancer

Disease stage

Required: Stage I

Grade: g1

Demographics

Ages 17–45
Female only

Prior therapy

Min 0 prior lines

Must have received: progesterone therapy — persistent lesions after one course (12 weeks) OR incomplete remission after 2 courses (24 weeks)

Patients with persistent lesions after one course (12 weeks) of progesterone therapy; Patients who did not achieve complete remission after 2 courses (24 weeks) of progesterone therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT05675787 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received progesterone therapy.

What disease stage is eligible?

Stage I is required.

Is there an age limit?

Yes. Patients must be 45 years or younger and at least 17 years old.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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