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OncoMatch/Clinical Trials/NCT05672108

Phase II Trial of Lung Chemoemobolization

Is NCT05672108 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including Ethiodized Oil and Mitomycin for lung non-small cell carcinoma.

Phase 2RecruitingCity of Hope Medical CenterNCT05672108Data as of May 2026

Treatment: Ethiodized Oil · Mitomycin · Tris-acryl Gelatin MicrospheresThis phase II trial evaluates how well transarterial chemoembolization (TACE) works for treating patients with non-small cell lung cancer or lung metastases. TACE is a minimally invasive procedure that involves injecting chemotherapy directly into an artery that supplies blood to tumors, and then blocking off the blood supply to the tumors. Mitomycin (chemotherapy), Lipiodol (drug carrier), and Embospheres (small plastic beads that block off the artery) are injected into the tumor-feeding artery. This traps the chemotherapy inside the tumor and also cuts off the tumor\'s blood supply. As a result, the tumor is exposed to a high dose of chemotherapy, and is also deprived of nutrients and oxygen. TACE can be effective at controlling or stopping the growth of lung tumors.

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Colorectal Cancer

Sarcoma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Lab requirements

Blood counts

Platelets < 50,000 (after transfusion, if needed); INR > 2 (after transfusion, if needed); Hemoglobin < 7 (after transfusion, if needed) [all excluded]

Kidney function

estimated glomerular filtration rate (eGFR) < 30 mL/min/1.73 m^2 [excluded]

Platelets < 50,000 (after transfusion, if needed); INR > 2 (after transfusion, if needed); Hemoglobin < 7 (after transfusion, if needed); Renal failure (eGFR < 30 mL/min/1.73 m^2)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • City of Hope Medical Center · Duarte, California
  • Memorial Sloan Kettering Cancer Center · New York, New York

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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