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OncoMatch/Clinical Trials/NCT05632809

REStoring lymphoCytes Using NKTR-255* After chemoradiothErapy in Solid Tumors (RESCUE)

Is NCT05632809 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including NKTR-255 and Durvalumab for lung cancer.

Phase 2RecruitingM.D. Anderson Cancer CenterNCT05632809Data as of May 2026

Treatment: NKTR-255 · DurvalumabTo learn about the effects of the investigational drug NKTR-255 in combination with the standard drug durvalumab on locally advanced NSCLC when given after CRT.

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Cannot have received: anti-PD-1 therapy

Prior exposure to any anti-PD-1 or anti-PD-L1 antibody.

Cannot have received: anti-PD-L1 therapy

Prior exposure to any anti-PD-1 or anti-PD-L1 antibody.

Cannot have received: IL-2

Prior exposure to IL-2 or IL-5.

Cannot have received: IL-5

Prior exposure to IL-2 or IL-5.

Lab requirements

Kidney function

cr < 2.5 limit of normal and cr clearance >30

Liver function

ast, alt, alk phos, and tbili <2 fold upper limit

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • M D Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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