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OncoMatch/Clinical Trials/NCT05613023

A Trial of 5 Fraction Prostate SBRT Versus 5 Fraction Prostate and Pelvic Nodal SBRT

Is NCT05613023 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies non-drug interventions for prostate cancer.

Phase 3RecruitingInstitute of Cancer Research, United KingdomNCT05613023Data as of May 2026

This study will compare the safety and efficacy of curative radiotherapy to the prostate and lymph glands given in 5 visits to that of prostate alone radiotherapy given in 5 visits, in men with high risk localised prostate cancer.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Disease stage

Grade: Gleason 8-10ISUP grade group 4ISUP grade group 5 (Gleason/ISUP)

High risk localised prostate cancer as defined by * Gleason 8-10 (grade groups 4 and 5) and/or * Stage T3a/b or T4

Performance status

WHO 0–2

Prior therapy

No prior treatment (treatment-naive required)

Cannot have received: active treatment for prostate cancer

Previous active treatment for prostate cancer

Cannot have received: chemotherapy

Exception: within 6 weeks of the start of radiotherapy

Patients who have had chemotherapy within 6 weeks of the start of radiotherapy.

Cannot have received: pelvic radiotherapy

prior pelvic radiotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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