OncoMatch

OncoMatch/Clinical Trials/NCT05613023

A Trial of 5 Fraction Prostate SBRT Versus 5 Fraction Prostate and Pelvic Nodal SBRT

Is NCT05613023 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies non-drug interventions for prostate cancer.

Phase 3RecruitingInstitute of Cancer Research, United KingdomNCT05613023Data as of Jun 2026Location: Ireland · New Zealand · United Kingdom

This study will compare the safety and efficacy of curative radiotherapy to the prostate and lymph glands given in 5 visits to that of prostate alone radiotherapy given in 5 visits, in men with high risk localised prostate cancer.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Disease stage

Grade: Gleason 8-10ISUP grade group 4ISUP grade group 5 (Gleason/ISUP)

High risk localised prostate cancer as defined by * Gleason 8-10 (grade groups 4 and 5) and/or * Stage T3a/b or T4

Performance status

WHO 0–2

Demographics

Male only

Prior therapy

No prior treatment (treatment-naive required)

Cannot have received: active treatment for prostate cancer

Previous active treatment for prostate cancer

Cannot have received: chemotherapy

Exception: within 6 weeks of the start of radiotherapy

Patients who have had chemotherapy within 6 weeks of the start of radiotherapy.

Cannot have received: pelvic radiotherapy

prior pelvic radiotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT05613023 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Is this trial open to female patients?

No. This trial enrolls male patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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