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OncoMatch/Clinical Trials/NCT05592626

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Is NCT05592626 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies STAR0602 for advanced solid tumors.

Phase 1/2RecruitingMarengo Therapeutics, Inc.NCT05592626Data as of May 2026

Treatment: STAR0602This is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent administered intravenously in participants with advanced solid tumors that are antigen-rich.

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Extracted eligibility criteria

Cancer type

Tumor Agnostic

Non-Small Cell Lung Carcinoma

Biomarker criteria

Allowed: KRAS wild-type

CRC (both Ras wild type and mutant)

Allowed: KRAS mutation

CRC (both Ras wild type and mutant)

Disease stage

Required: Stage III, IV, PRIMARY STAGE IV

unresectable, locally advanced, or metastatic

Prior therapy

Max 3 prior lines

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Loma Linda University Cancer Center · Loma Linda, California
  • UC Davis Comprehensive Cancer Center · Sacramento, California
  • Sarah Cannon Research Institute at HealthONE · Denver, Colorado
  • AdventHealth Celebration · Celebration, Florida
  • University of Miami Sylvester Comprehensive Cancer Center · Miami, Florida

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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