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OncoMatch/Clinical Trials/NCT05565118

Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression

Is NCT05565118 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies non-drug interventions for high grade glioma.

Phase 1RecruitingCase Comprehensive Cancer CenterNCT05565118Data as of May 2026

The purpose of this study is to test the safety and feasibility of recording brain activity within and around high-grade glioma tumors at the time of surgery. A small biopsy will be taken at the sites of the recordings.

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Extracted eligibility criteria

Cancer type

Glioblastoma

Disease stage

Required: Stage WHO GRADE 3, WHO GRADE 4 (WHO)

WHO Grade 3 and 4, including GBM

Lab requirements

Blood counts

Absolute neutrophil count ≥ 1500/µL; Platelets ≥ 100 000/µL; INR OR PT/aPTT ≤1.5 × ULN unless participant is receiving anticoagulant therapy as long as PT or aPTT is within therapeutic range of intended use of anticoagulants

Absolute neutrophil count ≥ 1500/µL; Platelets ≥ 100 000/µL; INR OR prothrombin time (PT) Activated partial thromboplastin time (aPTT) ≤1.5 × Upper limit of normal (ULN) unless participant is receiving anticoagulant therapy as long as PT or aPTT is within therapeutic range of intended use of anticoagulants

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center · Cleveland, Ohio

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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