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OncoMatch/Clinical Trials/NCT05557877

Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer

Is NCT05557877 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Low-Dose Aspirin for breast carcinoma.

Phase 2RecruitingMayo ClinicNCT05557877Data as of Jun 2026

Treatment: Low-Dose AspirinThis phase II trial tests whether low-dose aspirin can affect markers of inflammation in postpartum (after childbirth) women planning to have a breast biopsy. Chronic inflammation may increase the risk of postpartum related breast cancer. Low-dose aspirin is a non-steroidal anti-inflammatory drug. Giving low-dose aspirin may affect markers of inflammation in blood and tissue and may prevent postpartum related breast cancer.

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Extracted eligibility criteria

Treatments studied

Other

Low-Dose Aspirin

Cancer type

Breast Carcinoma

Demographics

Ages ≤ 45
Female only

Prior therapy

Cannot have received: systemic therapy for any other cancer

Received systemic treatment for any other cancer at any time

Cannot have received: systemic therapy for any prior or current malignancy

Any prior or current malignancy requiring prior or current systemic therapy

Lab requirements

Blood counts

Hemoglobin >= 9.0 g/dL (obtained <= 30 days prior to registration); Platelet count >= 100,000/mm^3 (obtained <= 30 days prior to registration)

Kidney function

Serum creatinine <= 2.0 mg/dl (obtained <= days prior to registration)

Hemoglobin >= 9.0 g/dL (obtained <= 30 days prior to registration); Platelet count >= 100,000/mm^3 (obtained <= 30 days prior to registration); Serum creatinine <= 2.0 mg/dl (obtained <= days prior to registration)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Mayo Clinic in Arizona · Scottsdale, Arizona
  • Mayo Clinic in Florida · Jacksonville, Florida
  • Indiana University Simon Comprehensive Cancer Center · Indianapolis, Indiana
  • Mayo Clinic in Rochester · Rochester, Minnesota

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT05557877 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior systemic therapy for any other cancer, systemic therapy for any prior or current malignancy disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 45 years or younger.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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