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OncoMatch/Clinical Trials/NCT05557877

Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer

Is NCT05557877 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Low-Dose Aspirin for breast carcinoma.

Phase 2RecruitingMayo ClinicNCT05557877Data as of May 2026

Treatment: Low-Dose AspirinThis phase II trial tests whether low-dose aspirin can affect markers of inflammation in postpartum (after childbirth) women planning to have a breast biopsy. Chronic inflammation may increase the risk of postpartum related breast cancer. Low-dose aspirin is a non-steroidal anti-inflammatory drug. Giving low-dose aspirin may affect markers of inflammation in blood and tissue and may prevent postpartum related breast cancer.

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Extracted eligibility criteria

Cancer type

Breast Carcinoma

Prior therapy

Cannot have received: systemic therapy for any other cancer

Received systemic treatment for any other cancer at any time

Cannot have received: systemic therapy for any prior or current malignancy

Any prior or current malignancy requiring prior or current systemic therapy

Lab requirements

Blood counts

Hemoglobin >= 9.0 g/dL (obtained <= 30 days prior to registration); Platelet count >= 100,000/mm^3 (obtained <= 30 days prior to registration)

Kidney function

Serum creatinine <= 2.0 mg/dl (obtained <= days prior to registration)

Hemoglobin >= 9.0 g/dL (obtained <= 30 days prior to registration); Platelet count >= 100,000/mm^3 (obtained <= 30 days prior to registration); Serum creatinine <= 2.0 mg/dl (obtained <= days prior to registration)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Mayo Clinic in Arizona · Scottsdale, Arizona
  • Mayo Clinic in Florida · Jacksonville, Florida
  • Indiana University Simon Comprehensive Cancer Center · Indianapolis, Indiana
  • Mayo Clinic in Rochester · Rochester, Minnesota

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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