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OncoMatch/Clinical Trials/NCT05557838

Study of Durvalumab Plus Tremelimumab as First-line Treatment in Chinese Patients With Unresectable Hepatocellular Carinoma

Is NCT05557838 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies multiple treatments including Durvalumab and Tremelimumab for hepatocellular carcinoma.

Phase 3RecruitingAstraZenecaNCT05557838Data as of Jun 2026Location: China

Treatment: Durvalumab · TremelimumabThis is a prospective, open label, multi-center, interventional study to assess the safety and efficacy of Druvalumab plus Tremelimumab as first-line treatment in Chinese patients with unresectable hepatocellular carcinoma.

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Extracted eligibility criteria

Treatments studied

Immunotherapy

DurvalumabTremelimumab

Cancer type

Hepatocellular Carcinoma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Lab requirements

Liver function

child-pugh score class a or b

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT05557838 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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