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OncoMatch/Clinical Trials/NCT05554302

Characterization of 18F-Fluciclovine PET Amino Acid Radiotracer in Resected Brain Metastasis

Is NCT05554302 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies 18F-Fluciclovine for brain metastases.

Phase 2RecruitingBaptist Health South FloridaNCT05554302Data as of May 2026

Treatment: 18F-FluciclovineThis study is for patients who have had surgery to remove brain metastasis and are planned to have stereotactic radiosurgery (SRS) after their brain surgery. It will be optional for patients to have a pre-surgery 18F-Fluciclovine PET/CT scan. The goal of the study is to determine whether a specific imaging agent, known as 18F-Fluciclovine, will help physicians evaluate the extent of surgery and determine if there is any visible tumor above what MRI alone can identify as well as improve the physicians' ability to detect recurring disease. This agent (18F-Fluciclovine) is investigational for the imaging of brain metastases.

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Extracted eligibility criteria

Cancer type

Glioblastoma

Disease stage

Metastatic disease required

Radiographic diagnosis of brain metastasis

Performance status

ECOG 0–3(Limited self-care)

Prior therapy

Cannot have received: whole-brain radiation therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Miami Cancer Institute at Baptist Health South Florida · Miami, Florida

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