OncoMatch/Clinical Trials/NCT05511623
Tislelizumab Combined With Concurrent Chemoradiotherapy as First-line Treatment for Stage IIIC2 Cervical Cancer
Is NCT05511623 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies tislelizumab for cervical cancer.
Treatment: tislelizumab — To evaluate the efficacy and safety of tislelizumab combined with concurrent chemoradiotherapy in first-line treatment of stage IIIC2 cervical cancer.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Immunotherapy
Cancer type
Cervical Cancer
Disease stage
Required: Stage IIIC2
Performance status
ECOG 0–1(Restricted strenuous activity)
Demographics
Prior therapy
Cannot have received: anti-PD-1 therapy
Previously treatment with PD-1 and/or PD-L1, or CTLA-4 antibody, or other medications targeting immunomodulatory receptors
Lab requirements
Blood counts
hemoglobin ≥90g/L, neutrophils ≥1.5×10^9/L, platelets ≥80×10^9/L
Kidney function
Creatinine clearance ≥60 mL/min
Liver function
Total bilirubin ≤1.5 x institutional upper limit of normal, AST(SGOT)/ALT(SGPT) ≤2.5 × institutional upper limit of normal, ALB≥30g/L
Participants must have normal organ and marrow function as defined below: (hemoglobin ≥90g/L, neutrophils ≥1.5×10^9/L, platelets ≥80×10^9/L, ALB≥30g/L, Total bilirubin≤1.5 x institutional upper limit of normal, AST(SGOT)/ALT(SGPT) ≤2.5 × institutional upper limit of normal, Creatinine clearance≥60 mL/min
Structured fields extracted by AI. May contain errors — verify against the official protocol.
Frequently asked questions
Is NCT05511623 currently recruiting?
Yes, this trial is currently recruiting patients.
Are there prior therapy exclusions?
Yes. Prior anti-PD-1 therapy disqualifies patients from enrollment.
What disease stage is eligible?
Stage IIIC2 is required.
Is there an age limit?
Yes. Patients must be 70 years or younger.
Is this trial open to male patients?
No. This trial enrolls female patients only.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages