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OncoMatch/Clinical Trials/NCT05474846

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

Is NCT05474846 recruiting? Yes, currently enrolling (Sep 2026). This Phase 2/3 trial studies multiple treatments including Melatonin and Methylphenidate for sleep.

Phase 2/3RecruitingM.D. Anderson Cancer CenterNCT05474846Data as of Sep 2026

Treatment: Melatonin · MethylphenidateTo learn if Cognitive Behavior Therapy (called CBT), combined with either Bright Light Therapy (called BLT), methylphenidate, and/or melatonin, can help improve sleep and other related symptoms such as fatigue, anxiety, and depression in cancer patients. This is an investigational study. In this study, BLT, Methylphenidate and Melatonin will be compared to their placebos.

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Extracted eligibility criteria

Treatments studied

Other

MelatoninMethylphenidate

Cancer type

Tumor Agnostic

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites.

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Frequently asked questions

Is NCT05474846 currently recruiting?

Yes, this trial is currently recruiting patients.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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