OncoMatch/Clinical Trials/NCT05463263
A Phase 1/2 Study of STP938 for Adult Subjects With Relapsed/Refractory B-Cell and T-Cell Lymphomas
Is NCT05463263 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies STP938 for lymphoma, b-cell.
Treatment: STP938 — The Phase 1 part of the study is a dose escalation of STP938 as monotherapy. The Phase 2 part of the study is cohort expansion of STP938 as a monotherapy in 5 different B and T cell lymphomas.
Check if I qualifyExtracted eligibility criteria
Cancer type
Non-Hodgkin Lymphoma
Performance status
ECOG 0–2(Ambulatory, capable of self-care)
Prior therapy
Cannot have received: radiation therapy
Exception: must have measurable disease outside of the radiation field
Prior radiation or surgical resection of their lymphoma without additional sites of measurable disease outside of the radiation field
Cannot have received: radiation therapy
Exception: must be >2 weeks prior to first dose
subjects who have received prior radiation or surgical resection of their lymphoma ≤2 weeks prior to the first dose of study drug
Cannot have received: systemic cancer treatments
Exception: must be >4 weeks before enrollment or >5 half-lives since completion of previous investigational therapy, whichever is shorter
Systemic cancer treatments, monoclonal antibody-directed therapies, other investigational agents within 4 weeks before enrollment, or <5 half-lives since completion of previous investigational therapy, whichever is shorter.
Lab requirements
Blood counts
adequate bone marrow function and coagulation
Kidney function
adequate renal function
Liver function
adequate hepatic function
Cardiac function
QTcF ≤470 msec based on averaged triplicate ECG readings at Screening Visit
Adequate organ function (bone marrow, hepatic, renal function and coagulation). Subjects with corrected QT interval >470 msec based on averaged triplicate electrocardiogram (ECG) readings at the Screening Visit using the QT interval corrected for heart rate using Fridericia's method (QTcF).
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Colorado Blood Cancer Institute · Denver, Colorado
- Florida Cancer Specialists · Sarasota, Florida
- Memorial Sloan Kettering · New York, New York
Showing up to 5 US sites. See all sites on ClinicalTrials.gov →
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