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OncoMatch/Clinical Trials/NCT05452005

Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer

Is NCT05452005 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies [18F]-αvβ6-BP for lung cancer.

Phase 1RecruitingUniversity of California, DavisNCT05452005Data as of May 2026

Treatment: [18F]-αvβ6-BPThis study investigates fluorine-18-AlphaVBeta6-BP (\[18F\]-αvβ6-BP) as a Positron Emission (PET) imaging agent in Non-Small Cell Lung Cancer (NSCLC) patients with brain metastases. Investigators hypothesize that \[18F\]-αvβ6-BP PET/Computed Tomography (CT) is a sensitive tool for disease assessment in patients with metastatic NSCLC, including those with brain metastases.

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Extracted eligibility criteria

Cancer type

Non-Small Cell Lung Carcinoma

Small Cell Lung Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Lab requirements

Kidney function

glomerular filtration rate (gfr) ≥ 60

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • The University of California Davis Comprehensive Cancer Center · Sacramento, California

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