OncoMatch/Clinical Trials/NCT05429632
Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT
Is NCT05429632 recruiting? Yes, currently enrolling (Jun 2026). This Phase 3 trial studies mocravimod for adult acute myeloid leukemia.
Treatment: mocravimod — This is a multi-center, randomized, double-blinded, placebo controlled trial.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Other
Cancer type
Acute Myeloid Leukemia
Performance status
ECOG 0–1(Restricted strenuous activity)
Demographics
Lab requirements
Kidney function
estimated creatinine clearance < 45 mL/min by the Cockcroft-Gault formula [excluded]
Liver function
aspartate aminotransferase (AST) and/or alanine aminotransferase (ALT) > 2.5 x upper limit of normal (ULN); or total bilirubin > 1.5 mg/dL [excluded]
Cardiac function
Cardiac dysfunction [excluded]
Cardiac/pulmonary/hepatic/renal dysfunction. Hepatic dysfunction as defined by aspartate aminotransferase (AST) and/or alanine aminotransferase (ALT) > 2.5 x upper limit of normal (ULN); or total bilirubin > 1.5 mg/dL. Renal dysfunction with estimated creatinine clearance < 45 mL/min by the Cockcroft-Gault formula
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- University of Alabama Hospital (UAB Hospital) · Birmingham, Alabama
- Banner MD Anderson Cancer Center · Gilbert, Arizona
- City of Hope Comprehensive Cancer Center - Duarte · Duarte, California
- University of California Los Angeles (UCLA) - David Geffen School of Medicine · Los Angeles, California
- UCHealth Cancer Care - Anschutz Medical Campus - University of Colorado Cancer Center · Aurora, Colorado
Showing up to 5 US sites.
See all sites on ClinicalTrials.gov →Frequently asked questions
Is NCT05429632 currently recruiting?
Yes, this trial is currently recruiting patients.
Is there an age limit?
Yes. Patients must be 75 years or younger.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages