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OncoMatch/Clinical Trials/NCT05419076

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

Official title: A Single Arm Phase II Study Assessing Efficacy of Stereotactic Radiosurgery (SRS) for Brain Metastasis (BM) From Small Cell Lung Cancer (SCLC)

Is NCT05419076 recruiting? Yes, currently enrolling (Oct 2026). This Phase 2 trial studies non-drug interventions for lung cancer.

Phase 2RecruitingMemorial Sloan Kettering Cancer CenterNCT05419076Data as of Oct 2026

The purpose of the study is to see if stereotactic radiosurgery/SRS is an effective treatment for people with a new diagnosis of brain metastases from small cell lung cancer/SCLC.

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Extracted eligibility criteria

Cancer type

Small Cell Lung Cancer

Disease stage

Metastatic disease required

Performance status

KPS/ECOG 60–100

Prior therapy

Cannot have received: brain-directed radiotherapy

Prior brain-directed radiotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Memorial Sloan Kettering at Basking Ridge · Basking Ridge, New Jersey
  • Memorial Sloan Kettering Monmouth · Middletown, New Jersey
  • Memorial Sloan Kettering Bergen · Montvale, New Jersey
  • Memorial Sloan Kettering Suffolk - Commack · Commack, New York
  • Memorial Sloan Kettering Westchester · Harrison, New York

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT05419076 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior brain-directed radiotherapy disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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