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OncoMatch/Clinical Trials/NCT05355051

A Phase II Study of the Combination of Azacitidine and Pembrolizumab for Patients Relapsed/Refractory Hodgkin's Lymphoma

Is NCT05355051 recruiting? Yes, currently enrolling (Sep 2026). This Phase 2 trial studies multiple treatments including Azacytidine and Pembrolizumab for hodgkin's lymphoma.

Phase 2RecruitingM.D. Anderson Cancer CenterNCT05355051Data as of Sep 2026

Treatment: Azacytidine · PembrolizumabThis study is a Phase II single-center clinical trial designed to assess the efficacy, safety, and tolerability of pembrolizumab in combination with the 7-day regimen of azacitidine for the treatment of relapsed/refractory HL.

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Extracted eligibility criteria

Treatments studied

Immunotherapy

Pembrolizumab

Other

Azacytidine

Cancer type

Hodgkin Lymphoma

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Demographics

Ages ≥ 1

Lab requirements

Kidney function

adequate renal function per age unless related to the disease

Liver function

total bilirubin < 2x upper limit of normal (uln) unless increase is due to gilbert's disease, and ast < 3x uln unless considered due to lymphoma involvement

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • MD Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT05355051 currently recruiting?

Yes, this trial is currently recruiting patients.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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