OncoMatch/Clinical Trials/NCT05343013
TAS-102 With or Without Celecoxib in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy
Is NCT05343013 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies TAS-102 for colorectal cancer.
Treatment: TAS-102 — To measure the level of circulating tumor DNA (ctDNA) in the blood of colorectal cancer patients after 6 months of receiving TAS-102 therapy. ctDNA is genetic material from tumor cells that can be found and measured in the blood.
Check if I qualifyExtracted eligibility criteria
Treatments studied
Other
Cancer type
Colorectal Cancer
Disease stage
Required: Stage II, III, IV
Performance status
ECOG 0–1(Restricted strenuous activity)
Prior therapy
Must have received: platinum-based chemotherapy (oxaliplatin) — adjuvant
has completed all planned curative intent therapies that must include 3 months of oxaliplatin containing chemotherapy
Lab requirements
Blood counts
absolute neutrophil count: 1,000/mcL; platelets: 100,000/mcL
Kidney function
Serum creatinine 1.5 00 ULN or creatinine clearance 60 mL/min
Liver function
total bilirubin: institutional upper limit of normal (ULN); AST(SGOT)/ALT(SGPT): 3 0 institutional ULN
Has adequate organ and marrow function as defined below: 1. absolute neutrophil count: 1,000/mcL 2. platelets: 100,000/mcL 3. total bilirubin: institutional upper limit of normal (ULN) 4. AST(SGOT)/ALT(SGPT): 3 00 institutional ULN 5. Serum creatinine 1.5 00 ULN or creatinine clearance 60 mL/min.
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- MD Anderson Cancer Center · Houston, Texas
Showing up to 5 US sites.
See all sites on ClinicalTrials.gov →Frequently asked questions
Is NCT05343013 currently recruiting?
Yes, this trial is currently recruiting patients.
Is prior treatment required for enrollment?
Yes. Patients must have previously received platinum-based chemotherapy.
What disease stage is eligible?
Stage II or III or IV is required.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages