OncoMatch/Clinical Trials/NCT05327647
A Phase II Trial of Bicalutamide in Patients Receiving Intravesical BCG for Non-muscle Invasive Bladder Cancer
Is NCT05327647 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Bicalutamide for non-muscle invasive bladder cancer.
Treatment: Bicalutamide — This is a phase II randomized controlled clinical trial comparing standard induction BCG versus bicalutamide and standard induction BCG among patients with non-muscle invasive bladder cancer.
Check if I qualifyExtracted eligibility criteria
Cancer type
Urothelial Carcinoma
Prior therapy
Must have received: intravesical BCG induction — recommended by urologist
Patients have been recommended for a course of intravesical BCG induction treatment by their urologist
Cannot have received: induction BCG therapy
Patients who have received induction BCG therapy within the last 5 years will be ineligible for enrolment.
Lab requirements
Liver function
Patients with a history of liver disease whose hepatic enzymes, alkaline phosphatase or bilirubin are greater than twice the upper limit of normal will be ineligible.
Cardiac function
history of myocardial infarction or hospital admission for heart failure within the previous 12 months or unstable cardiovascular status will be ineligible; uncontrolled hypertension (systolic blood pressure > 160 documented on 2 occasions despite appropriate medical therapy) will be ineligible.
Patients with a history of myocardial infarction or hospital admission for heart failure within the previous 12 months or who have unstable cardiovascular status will be ineligible. Patients who have uncontrolled hypertension (for our purposes, defined as those having a systolic blood pressure > 160 documented on 2 occasions despite appropriate medical therapy) will similarly be ineligible. Patients with a history of liver disease whose hepatic enzymes, alkaline phosphatase or bilirubin are greater than twice the upper limit of normal will be ineligible.
Structured fields extracted by AI. May contain errors — verify against the official protocol.
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