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OncoMatch/Clinical Trials/NCT05250648

Clinical Trial on HIPEC with Mitomycin C in Colon Cancer Peritoneal Metastases (GECOP-MMC)

Is NCT05250648 recruiting? Yes, currently enrolling (May 2026). This Phase 4 trial studies complete cytoreductive surgery plus HIPEC with Mytomicin C for 90 minutes for peritoneal carcinomatosis.

Phase 4RecruitingHospital Universitario de FuenlabradaNCT05250648Data as of May 2026

Treatment: complete cytoreductive surgery plus HIPEC with Mytomicin C for 90 minutesThe aim of this study is to assess whether there are differences in PERITONEAL RECURRENCE in patients with Colon Cancer Peritoneal Metastases treated with complete surgical resection and systemic chemotherapy, with (Group 1) or without (Group 2) HIPEC with Mitomycin-C.

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Extracted eligibility criteria

Cancer type

Ovarian Cancer

Colorectal Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Must have received: systemic chemotherapy — perioperative (before and/or after surgery)

Treatment with perioperative systemic chemotherapy (SCT), before and/or after surgical procedure.

Cannot have received: HIPEC

Patients previously treated with HIPEC.

Lab requirements

Blood counts

No severe alterations in hematological function (operable patients)

Kidney function

No severe alterations in renal function (operable patients)

Liver function

No severe alterations in hepatic function (operable patients)

Cardiac function

No severe alterations in cardiac function (operable patients)

No severe alterations in hematological, renal, cardiac, pulmonary or hepatic function (operable patients).

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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