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OncoMatch/Clinical Trials/NCT05241249

Stimulation With Bethanechol in Combination With Gemcitabine and Nab-paclitaxel in Pancreatic Adenocarcinoma

Is NCT05241249 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including Bethanechol and Gemcitabine for pancreas cancer.

Phase 2RecruitingSusan E. BatesNCT05241249Data as of May 2026

Treatment: Bethanechol · Gemcitabine · nab-paclitaxelThe primary objective of this study is to assess the impact of bethanechol therapy on R0 resection rates. The safety objective will be assessment of the safety and tolerability of bethanechol in combination with gemcitabine and nab-paclitaxel. The exploratory objective will be to evaluate genomic biomarkers associated with parasympathetic stimulation in pancreatic cancer, and the ability to reduce tumor growth rate.

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Cancer type

Pancreatic Cancer

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Columbia University Medical Center · New York, New York

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