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OncoMatch/Clinical Trials/NCT05241093

A Study of HYML-122 and Cytarabine in Patients With FLT3 Positive Relapsed or Refractory Acute Myeloid Leukemia (AML)

Is NCT05241093 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies HYML-122; cytarabine for relapsed or refractory acute myeloid leukemia (aml).

Phase 2RecruitingTarapeutics Science Inc.NCT05241093Data as of May 2026

Treatment: HYML-122; cytarabineThis is a single-arm, open, multicenter, phase 2 study to evaluate the efficacy, safety and pharmacokinetics of HYLM-122 in combination with cytarabine in Chinese subjects with FLT3 positive relapsed or refractory acute myeloid leukemia.

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Extracted eligibility criteria

Cancer type

Acute Myeloid Leukemia

Biomarker criteria

Required: FLT3 mutation

Disease stage

Required: Stage RELAPSED, REFRACTORY

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Min 1 prior line

Must have received: induction chemotherapy

Refractory to at least 1 cycle of induction chemotherapy. Relapsed after achieving remission with a prior therapy.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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