OncoMatch/Clinical Trials/NCT05235165
Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma
Is NCT05235165 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies non-drug interventions for metastatic malignant neoplasm in the lung.
This phase III trial compares the effect of open thoracic surgery (thoracotomy) to thoracoscopic surgery (video-assisted thoracoscopic surgery or VATS) in treating patients with osteosarcoma that has spread to the lung (pulmonary metastases). Open thoracic surgery is a type of surgery done through a single larger incision (like a large cut) that goes between the ribs, opens up the chest, and removes the cancer. Thoracoscopy is a type of chest surgery where the doctor makes several small incisions and uses a small camera to help with removing the cancer. This trial is being done evaluate the two different surgery methods for patients with osteosarcoma that has spread to the lung to find out which is better.
Check if I qualifyExtracted eligibility criteria
Cancer type
Tumor Agnostic
Osteosarcoma
Disease stage
Metastatic disease required
Prior therapy
Must have received: systemic therapy (cisplatin-doxorubicin, ifosfamide-based drug regimens) — newly diagnosed or initial primary tumor
systemic therapy considered by the treating physician to be standard treatment for newly diagnosed osteosarcoma (eg, cisplatin-doxorubicin or ifosfamide-based drug regimens)
Cannot have received: therapeutic pulmonary surgery for lung metastasis
Patients who received therapeutic pulmonary surgery for lung metastasis prior to enrollment.
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Children's Hospital of Alabama · Birmingham, Alabama
- Providence Alaska Medical Center · Anchorage, Alaska
- Kingman Regional Medical Center · Kingman, Arizona
- Banner Children's at Desert · Mesa, Arizona
- Phoenix Childrens Hospital · Phoenix, Arizona
Showing up to 5 US sites. See all sites on ClinicalTrials.gov →
Could you qualify for this trial?
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