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OncoMatch/Clinical Trials/NCT05213884

The Efficacy of Induction and Adjuvant Camrelizumab Combined With Chemoradiation for LA-HNSCC

Is NCT05213884 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies multiple treatments including Camrelizumab and Concurrent cisplatin chemotherapy for head and neck squamous cell carcinoma.

Phase 2RecruitingChongqing University Cancer HospitalNCT05213884Data as of May 2026

Treatment: Camrelizumab · Concurrent cisplatin chemotherapyThis is a phase 2, single-arm clinical trial, with the purpose to evaluate the therapeutic efficacy and safety of PD-1 Blockade camrelizumab combined with induction chemotherapy followed by concurrent chemoradiotherapy and as adjuvant monotherapy in patients with locally advanced head and neck squamous cell carcinoma.

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Extracted eligibility criteria

Cancer type

Head and Neck Squamous Cell Carcinoma

Disease stage

Required: Stage III, IVA, IVB

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Cannot have received: anti-PD-1 therapy

Prior therapy with a PD-1, anti-PD-Ligand 1 (PD-L1) or CTLA-4 agent.

Lab requirements

Blood counts

Adequate bone marrow function.

Kidney function

Adequate renal function.

Liver function

Adequate liver function.

Adequate bone marrow function. Adequate renal and liver function.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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