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OncoMatch/Clinical Trials/NCT05200260

Surgery Combined With Maintenance Targeted Therapy in the Treatment of Advanced Ovarian Cancer

Is NCT05200260 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies multiple treatments including PARP inhibitor and Bevacizumab for ovarian cancer.

Phase 2RecruitingShanghai Gynecologic Oncology GroupNCT05200260Data as of Jun 2026Location: China

Treatment: PARP inhibitor · BevacizumabOptimal Timing of Surgery combined with Maintenance Therapy in the Front-line Treatment of Advanced Ovarian Cancer

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Extracted eligibility criteria

Treatments studied

Targeted therapy

Bevacizumab

Other

PARP inhibitor

Cancer type

Ovarian Cancer

Biomarker criteria

Required: BRCA1 any tested

Required: BRCA2 any tested

Disease stage

Required: Stage IIIC, IV

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Demographics

Female only

Lab requirements

Blood counts

white blood cells >3,000/µl, absolute neutrophil count ≥1,500/µl, platelets ≥100,000/µl, hemoglobin ≥9 g/dl

Kidney function

serum creatinine <1.25 x upper normal limit (unl) or creatinine clearance ≥60 ml/min according to cockroft-gault formula or to local lab measurement

Liver function

serum bilirubin <1.25 x unl, ast(sgot) and alt(sgpt) <2.5 x unl

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT05200260 currently recruiting?

Yes, this trial is currently recruiting patients.

Does this trial require BRCA1?

Yes, BRCA1 any tested is a required biomarker for enrollment.

Does this trial require BRCA2?

Yes, BRCA2 any tested is a required biomarker for enrollment.

What disease stage is eligible?

Stage IIIC or IV is required.

Is this trial open to male patients?

No. This trial enrolls female patients only.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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