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OncoMatch/Clinical Trials/NCT05195710

Preoperative Y-90 Radioembolization for Tumor Control and Future Liver Remnant Hypertrophy in Patients With Colorectal Liver Metastases

Is NCT05195710 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1 trial studies Yttrium-90 (Y-90) resin microspheres for metastases.

Phase 1RecruitingM.D. Anderson Cancer CenterNCT05195710Data as of Jun 2026

Treatment: Yttrium-90 (Y-90) resin microspheresA prospective, interventional study evaluating the safety of Y-90 TARE for tumor control of the right side and induction of left liver hypertrophy as part of a planned single-stage or two-stage hepatectomy for patients with CLM and insufficient FLR at the time of presentation.

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Extracted eligibility criteria

Treatments studied

Other

Yttrium-90 (Y-90) resin microspheres

Disease stage

Metastatic disease required

Prior therapy

Must have received: cytotoxic chemotherapy

Received at least four cycles (or two months) of chemotherapy

Lab requirements

Blood counts

Platelet count ≥100,000/µL

Liver function

Starting total bilirubin ≤1.3 mg/dL (except if patient has Gilbert's Disease); no portal hypertension and/or cirrhosis; albumin ≥3.5 g/dl

Portal hypertension and/or cirrhosis; Starting total bilirubin >1.3 mg/dL (except if patient has Gilbert's Disease); Platelet count <100,000/µL; Albumin <3.5 g/dl

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • M D Anderson Cancer Center · Houston, Texas

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See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT05195710 currently recruiting?

Yes, this trial is currently recruiting patients.

Is prior treatment required for enrollment?

Yes. Patients must have previously received cytotoxic chemotherapy.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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