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OncoMatch/Clinical Trials/NCT05192122

Free From Maintenance Drug Therapy in Multiple Myeloma (The FREEDMM Trial) for Minimal Residual Disease (MRD

Is NCT05192122 recruiting? Yes, currently enrolling (May 2026). This Phase 1 trial studies non-drug interventions for multiple myeloma.

Phase 1RecruitingUniversity of Illinois at ChicagoNCT05192122Data as of May 2026

A pilot study to assess the risk of progression after stopping post-autologous stem cell transplant (ASCT) maintenance therapy in Minimal Residual Disease (MRD)-negative MM patients.

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Extracted eligibility criteria

Cancer type

Multiple Myeloma

Disease stage

Required: Stage R-ISS I, R-ISS II, R-ISS III (Revised International Staging System (R-ISS))

Revised International Staging System (R-ISS) I,2 or 3

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

Must have received: maintenance therapy after ASCT — post-ASCT

Received at least 2 years of post ASCT maintenance (patients may have received any number of prior lines of therapy).

Cannot have received: allogeneic hematopoietic cell transplant

Prior allogeneic hematopoietic cell transplant

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Illinois Cancer Center · Chicago, Illinois

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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