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OncoMatch/Clinical Trials/NCT05183126

Pharmacokinetic Study of Skeletal Muscle Area-based Paclitaxel Infusion in Patients With Cancer

Is NCT05183126 recruiting? Yes, currently enrolling (May 2026). This Phase 4 trial studies multiple treatments including Paclitaxel and Paclitaxel for breast cancer.

Phase 4RecruitingUniversity of Michigan Rogel Cancer CenterNCT05183126Data as of May 2026

Treatment: Paclitaxel · PaclitaxelThe primary objective of this pharmacokinetics study is to compare the maximum concentration level of paclitaxel in patients with low/sarcopenic skeletal muscle area (SMA), at the end of a 2-3 hour paclitaxel infusion, to the maximum level in patients with normal SMA at the end of a standard 1-hour infusion with the goal of determining whether lengthening the infusion in patients with low/sarcopenic SMA normalizes the levels to those of patients with normal SMA.

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Extracted eligibility criteria

Cancer type

Breast Carcinoma

Gastric Cancer

Esophageal Carcinoma

Disease stage

Metastatic disease required

Metastatic Gastric Cancer

Lab requirements

Blood counts

Adequate organ function to receive paclitaxel treatment as defined in the protocol

Kidney function

Adequate organ function to receive paclitaxel treatment as defined in the protocol

Liver function

Adequate organ function to receive paclitaxel treatment as defined in the protocol

Adequate organ function to receive paclitaxel treatment as defined in the protocol

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Michigan Rogel Cancer Center · Ann Arbor, Michigan

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