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OncoMatch/Clinical Trials/NCT05156060

Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer

Is NCT05156060 recruiting? Yes, currently enrolling (Jun 2026). This Phase 1/2 trial studies multiple treatments including Gabapentin and Ketamine for head and neck cancer.

Phase 1/2RecruitingNatalie LockneyNCT05156060Data as of Jun 2026

Treatment: Gabapentin · KetamineThis is a study to establish a safe and feasible dose for prophylactic use of a combination of gabapentin and ketamine in head and neck cancer patients undergoing chemoradiation.

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Extracted eligibility criteria

Treatments studied

Other

GabapentinKetamine

Cancer type

Head and Neck Squamous Cell Carcinoma

Disease stage

Required: Stage T3N0M0, T4N0M0, T1N1M0, T2N1M0, T3N1M0, T4N1M0, T1N2M0, T2N2M0, T3N2M0, T4N2M0, T1N3M0, T2N3M0, T3N3M0, T4N3M0 (TNM)

Locally advanced non-metastatic disease (T3N0M0, T4N0M0, T1-4N1-3M0)

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Demographics

Ages ≥ 21

Lab requirements

Kidney function

glomerular filtration rate <30 mL/min/1.73 m2 [excluded]

Glomerular filtration rate <30 mL/min/1.73 m2

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Vanderbilt-Ingram Cancer Center · Nashville, Tennessee

Showing up to 5 US sites.

See all sites on ClinicalTrials.gov →

Frequently asked questions

Is NCT05156060 currently recruiting?

Yes, this trial is currently recruiting patients.

What disease stage is eligible?

Stage T3N0M0 or T4N0M0 or T1N1M0 or T2N1M0 or T3N1M0 or T4N1M0 or T1N2M0 or T2N2M0 or T3N2M0 or T4N2M0 or T1N3M0 or T2N3M0 or T3N3M0 or T4N3M0 is required.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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