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OncoMatch/Clinical Trials/NCT05156060

Gabapentin & Ketamine for Prevention/Treatment of Acute/Chronic Pain in Locally Advanced Head and Neck Cancer

Is NCT05156060 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies multiple treatments including Gabapentin and Ketamine for head and neck cancer.

Phase 1/2RecruitingNatalie LockneyNCT05156060Data as of May 2026

Treatment: Gabapentin · KetamineThis is a study to establish a safe and feasible dose for prophylactic use of a combination of gabapentin and ketamine in head and neck cancer patients undergoing chemoradiation.

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Extracted eligibility criteria

Cancer type

Head and Neck Squamous Cell Carcinoma

Disease stage

Required: Stage T3N0M0, T4N0M0, T1N1M0, T2N1M0, T3N1M0, T4N1M0, T1N2M0, T2N2M0, T3N2M0, T4N2M0, T1N3M0, T2N3M0, T3N3M0, T4N3M0 (TNM)

Locally advanced non-metastatic disease (T3N0M0, T4N0M0, T1-4N1-3M0)

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Lab requirements

Kidney function

glomerular filtration rate <30 mL/min/1.73 m2 [excluded]

Glomerular filtration rate <30 mL/min/1.73 m2

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Vanderbilt-Ingram Cancer Center · Nashville, Tennessee

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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