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OncoMatch/Clinical Trials/NCT05109494

Hypofractionated vs Conventional Fractionated RT in Soft Tissue Sarcomas

Is NCT05109494 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies non-drug interventions for soft tissue sarcoma.

Phase 2RecruitingUniversity of Wisconsin, MadisonNCT05109494Data as of May 2026

This research study is designed to find out if radiation therapy treatment prior to surgery is safe and effective to treat soft tissue sarcomas. 30 participants with soft tissue sarcoma will be enrolled and can expect to be on study for up to 5 years.

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Extracted eligibility criteria

Cancer type

Sarcoma

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: sarcoma-directed chemotherapy

No prior sarcoma-directed chemotherapy

Cannot have received: radiation therapy

No prior sarcoma-directed ... radiotherapy

Lab requirements

Blood counts

absolute neutrophil count > 500/mcl, hemoglobin > 8 g/dl, platelets > 50,000/mcl

Kidney function

creatinine clearance > 30 ml/min

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • University of Wisconsin Hospital and Clinics · Madison, Wisconsin

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