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OncoMatch/Clinical Trials/NCT05100095

Hypofractionated Radiation Therapy for Merkel Cell Carcinoma

Is NCT05100095 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Radiation therapy for merkel cell carcinoma.

Phase 2RecruitingM.D. Anderson Cancer CenterNCT05100095Data as of May 2026

Treatment: Radiation therapyThis phase II trial tests whether hypofractionated radiation works to treat patients with Merkel cell carcinoma. Radiation therapy uses high energy radio waves to kill cancer cells and shrink tumors. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may be more convenient for patients and less immunosuppressive.

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Extracted eligibility criteria

Cancer type

Tumor Agnostic

Performance status

ECOG 0–3(Limited self-care)

Prior therapy

Cannot have received: radiation therapy

Exception: prior RT to the site of planned primary or nodal radiation treatment such that the prior site of treatment would be encompassed by the radiation field needed to treat the current cancer

Previous radiation therapy to the site of planned primary or nodal radiation treatment such that the prior site of treatment would be encompassed by the radiation field needed to treat the current cancer. In other words, treatment on this trial would require re-irradiation of tissues.

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • M D Anderson Cancer Center · Houston, Texas

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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