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OncoMatch/Clinical Trials/NCT05093907

A Study to Evaluate Safety and Efficacy of BEY1107 in Combination with Capecitabine in Patients with Metastatic Colorectal Cancer

Is NCT05093907 recruiting? Yes, currently enrolling (May 2026). This Phase 1/2 trial studies multiple treatments including BEY1107 and Capecitabine for metastatic colorectal cancer.

Phase 1/2RecruitingBeyondBio Inc.NCT05093907Data as of May 2026

Treatment: BEY1107 · CapecitabineThis is a Phase 1/2 study to evaluate the maximum tolerated dose, safety and efficacy of BEY1107 in combination with capecitabine in patients with metastatic colorectal cancer refractory or intolerant to standard of care (SoC).

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Extracted eligibility criteria

Cancer type

Colorectal Cancer

Disease stage

Metastatic disease required

Performance status

ECOG 0–1(Restricted strenuous activity)

Prior therapy

Min 2 prior lines

Must have received: chemotherapy (fluoropyrimidine, oxaliplatin, irinotecan) — second-line or beyond

Patients who experienced treatment failure of colorectal cancer with the second-line or beyond standard chemotherapy (including fluoropyrimidine, oxaliplatin and irinotecan)

Cannot have received: radiation therapy

Patients who received radiation therapy, chemotherapy or biological agent including hormone therapy recently

Cannot have received: chemotherapy

Patients who received radiation therapy, chemotherapy or biological agent including hormone therapy recently

Cannot have received: biological agent

Patients who received radiation therapy, chemotherapy or biological agent including hormone therapy recently

Cannot have received: hormone therapy

Patients who received radiation therapy, chemotherapy or biological agent including hormone therapy recently

Cannot have received: other investigational product

Subjects who had been administered other IP within 4 weeks prior to screening

Lab requirements

Blood counts

laboratory findings of inadequate bone marrow function excluded

Kidney function

laboratory findings of inadequate kidney function excluded

Liver function

laboratory findings of inadequate liver function excluded

Subjects who has labortory findings of inadequate bone marrow, kidney and liver function

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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