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OncoMatch/Clinical Trials/NCT05050929

RAPid SimPLE Targeted Radiation Treatment for Brain Metastases

Is NCT05050929 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies non-drug interventions for brain metastases, adult.

Phase 2RecruitingBritish Columbia Cancer AgencyNCT05050929Data as of Jun 2026Location: Canada

The aim of the study is to show that rapid, simple targeted radiotherapy to brain metastases with 8 Gy / 1 is non-inferior to 20 Gy / 5 in terms of overall survival for patients with poor prognosis.

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Extracted eligibility criteria

Disease stage

Metastatic disease required

Demographics

Ages ≤ 100

Prior therapy

Cannot have received: whole brain radiation therapy

Exception: if less than 3 months prior to randomization

WBRT less than 3 months prior to randomization

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT05050929 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior whole brain radiation therapy disqualifies patients from enrollment.

Is there an age limit?

Yes. Patients must be 100 years or younger.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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