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OncoMatch/Clinical Trials/NCT05050929

RAPid SimPLE Targeted Radiation Treatment for Brain Metastases

Is NCT05050929 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies non-drug interventions for brain metastases, adult.

Phase 2RecruitingBritish Columbia Cancer AgencyNCT05050929Data as of May 2026

The aim of the study is to show that rapid, simple targeted radiotherapy to brain metastases with 8 Gy / 1 is non-inferior to 20 Gy / 5 in terms of overall survival for patients with poor prognosis.

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Extracted eligibility criteria

Disease stage

Metastatic disease required

Prior therapy

Cannot have received: whole brain radiation therapy

Exception: if less than 3 months prior to randomization

WBRT less than 3 months prior to randomization

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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