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OncoMatch/Clinical Trials/NCT05045066

Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients

Is NCT05045066 recruiting? Yes, currently enrolling (May 2026). This Early Phase 1 trial studies non-drug interventions for localized prostate carcinoma.

Early Phase 1RecruitingMayo ClinicNCT05045066Data as of May 2026

This early phase I is to find out how common vitamin D insufficiency is among African American patients with a history of prostate cancer that has not spread to other parts of the body (localized) or has spread to other places in the body (metastatic) and how vitamin D insufficiency affects the immune system. This study also aims to find out if replacing vitamin D results in normalization of the immune function. Information from this study may benefit prostate cancer patients by identifying vitamin D insufficiency which in several studies had been found to contribute to more aggressive prostate cancers.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Disease stage

Required: Stage LOCALIZED, IV, LOCALLY RECURRENT (AJCC v8)

Localized Prostate Carcinoma; Stage IV Prostate Cancer AJCC v8; Locally Recurrent Prostate Carcinoma; Metastatic Prostate Carcinoma

Prior therapy

Cannot have received: chemotherapy

Chemotherapy or surgery or radiation within the last 3 weeks prior to blood collection

Cannot have received: surgery

Chemotherapy or surgery or radiation within the last 3 weeks prior to blood collection

Cannot have received: radiation therapy

Chemotherapy or surgery or radiation within the last 3 weeks prior to blood collection

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Mayo Clinic in Arizona · Scottsdale, Arizona
  • Mayo Clinic in Florida · Jacksonville, Florida

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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