OncoMatch/Clinical Trials/NCT05045066
Immunological Effects of Vitamin D Replacement Among Black/African American Prostate Cancer Patients
Is NCT05045066 recruiting? Yes, currently enrolling (Jun 2026). This Early Phase 1 trial studies non-drug interventions for localized prostate carcinoma.
This early phase I is to find out how common vitamin D insufficiency is among African American patients with a history of prostate cancer that has not spread to other parts of the body (localized) or has spread to other places in the body (metastatic) and how vitamin D insufficiency affects the immune system. This study also aims to find out if replacing vitamin D results in normalization of the immune function. Information from this study may benefit prostate cancer patients by identifying vitamin D insufficiency which in several studies had been found to contribute to more aggressive prostate cancers.
Check if I qualifyExtracted eligibility criteria
Cancer type
Prostate Cancer
Disease stage
Required: Stage LOCALIZED, IV, LOCALLY RECURRENT (AJCC v8)
Localized Prostate Carcinoma; Stage IV Prostate Cancer AJCC v8; Locally Recurrent Prostate Carcinoma; Metastatic Prostate Carcinoma
Demographics
Prior therapy
Cannot have received: chemotherapy
Chemotherapy or surgery or radiation within the last 3 weeks prior to blood collection
Cannot have received: surgery
Chemotherapy or surgery or radiation within the last 3 weeks prior to blood collection
Cannot have received: radiation therapy
Chemotherapy or surgery or radiation within the last 3 weeks prior to blood collection
Structured fields extracted by AI. May contain errors — verify against the official protocol.
US trial sites
- Mayo Clinic in Arizona · Scottsdale, Arizona
- Mayo Clinic in Florida · Jacksonville, Florida
Showing up to 5 US sites.
See all sites on ClinicalTrials.gov →Frequently asked questions
Is NCT05045066 currently recruiting?
Yes, this trial is currently recruiting patients.
Are there prior therapy exclusions?
Yes. Prior chemotherapy, surgery, radiation therapy disqualifies patients from enrollment.
What disease stage is eligible?
Stage LOCALIZED or IV or LOCALLY RECURRENT is required.
Is this trial open to female patients?
No. This trial enrolls male patients only.
Could you qualify for this trial?
Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.
Check if I qualifyRelated pages