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OncoMatch/Clinical Trials/NCT05035147

Albumin-bound Paclitaxel Combined With Gemcitabine First-line Inoperable Pancreatic Cancer

Is NCT05035147 recruiting? Yes, currently enrolling (Jun 2026). This Phase 4 trial studies albumin-bound paclitaxel for pancreatic cancer.

Phase 4RecruitingTianjin Medical University Cancer Institute and HospitalNCT05035147Data as of Jun 2026Location: China

Treatment: albumin-bound paclitaxelThis study aims to further observe and evaluate whether the three-week administration of albumin-bound paclitaxel combined with gemcitabine is equivalent to the four-week administration in the treatment of inoperable locally advanced or metastatic pancreatic cancer

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Extracted eligibility criteria

Treatments studied

Chemotherapy

albumin-bound paclitaxel

Cancer type

Pancreatic Cancer

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Lab requirements

Blood counts

Hb ≥90 g/L (no blood transfusion within 14 days); ANC ≥1.5×10^9/L; PLT ≥100×10^9/L

Kidney function

Cr ≤1.5x ULN or creatinine clearance rate ≥60 ml/min

Liver function

TBIL <1.5x ULN; ALT and AST ≤3x ULN, <5x ULN if liver metastasis

The main organs are functioning normally, that is, they meet the following standards: Routine blood examination: Hb≥90g/L (no blood transfusion within 14 days); ANC ≥1.5×109/L; PLT ≥100×109/L; Biochemical examination: ALB≥29 g/L (without ALB in 14 days), TBIL <1.5 times the upper limit of normal (ULN); ALT and AST≤3ULN, accompanied by liver metastasis, then ALT and AST<5×ULN; Cr ≤1.5×ULN or creatinine clearance rate ≥60ml/min;

Structured fields extracted by AI. May contain errors — verify against the official protocol.

Frequently asked questions

Is NCT05035147 currently recruiting?

Yes, this trial is currently recruiting patients.

Can patients have received prior systemic therapy?

No. This trial requires treatment-naive patients — prior systemic therapy is an exclusion criterion.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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