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OncoMatch/Clinical Trials/NCT05029063

Primary Thromboprophylaxis in Patients With Malignancy and Central Venous Catheters

Is NCT05029063 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies Rivaroxaban 10 MG for venous thromboembolism.

Phase 3RecruitingOttawa Hospital Research InstituteNCT05029063Data as of May 2026

Treatment: Rivaroxaban 10 MGThe purpose of the full trial is to determine the efficacy and safety of prophylactic dose rivaroxaban to prevent VTE among cancer patients with CVC.

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Extracted eligibility criteria

Lab requirements

Blood counts

No known thrombocytopenia (platelet count < 50x 10^9/L) in the previous 3 months

Kidney function

No severe renal insufficiency (Creatinine clearance <30 mL/min (defined by Cockcroft-Gault) in the previous 3 months)

Liver function

No documented severe liver disease (e.g., acute clinical hepatitis, chronic active hepatitis or cirrhosis) in the previous 3 months

Severe renal insufficiency (Creatinine clearance <30 mL/min (defined by Cockcroft-Gault) in the previous 3 months); Documented severe liver disease (e.g., acute clinical hepatitis, chronic active hepatitis or cirrhosis) in the previous 3 months; Known thrombocytopenia (platelet count < 50x 10^9/L) in the previous 3 months

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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