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OncoMatch/Clinical Trials/NCT05020912

Alteration of the Immune Microenvironment in Basal Cell Carcinoma Following Photodynamic Therapy

Is NCT05020912 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies ALA for basal cell carcinoma.

Phase 2RecruitingCase Comprehensive Cancer CenterNCT05020912Data as of May 2026

Treatment: ALAThe purpose of this study is to better understand the immune response to basal cell carcinoma (BCC) treated with Photodynamic Therapy (PDT) in order to develop new methods of treating BCC. Previous research suggests that PDT alters the immune response, possibly in a way that could promote better tumor clearance when combined with other treatments. Overall, participation in this study will help the study team better understand the anti-tumor immune response when BCC is treated with PDT.

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Extracted eligibility criteria

Cancer type

Tumor Agnostic

Prior therapy

Cannot have received: medical or radiation therapy for other cancers

Currently being treated for other cancers with medical or radiation therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Cleveland Clinic, Case Comprehensive Cancer Center · Cleveland, Ohio

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