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OncoMatch/Clinical Trials/NCT05013892

NTS-WBRT in Brain Metastases

Is NCT05013892 recruiting? Yes, currently enrolling (Jun 2026). This Phase 2 trial studies Memantine for brain metastases.

Phase 2RecruitingMassachusetts General HospitalNCT05013892Data as of Jun 2026

Treatment: MemantineThis research is being done to assess the quality of life and symptom burden in participants who receive (normal tissue sparing whole brain radiation therapy (NTS-WBRT). This research study involves: * NTS-WBRT (normal tissue sparing whole brain radiation therapy) * Memantine standard of care drug

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Extracted eligibility criteria

Treatments studied

Other

Memantine

Disease stage

Metastatic disease required

Prior therapy

Cannot have received: whole brain radiation therapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Massachusetts General Hospital Cancer Center · Boston, Massachusetts

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Frequently asked questions

Is NCT05013892 currently recruiting?

Yes, this trial is currently recruiting patients.

Are there prior therapy exclusions?

Yes. Prior whole brain radiation therapy disqualifies patients from enrollment.

Could you qualify for this trial?

Enter your biomarker results to see how this trial's eligibility criteria match your specific cancer profile.

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