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OncoMatch/Clinical Trials/NCT04987463

Efficacy and Safety of Rapamycin Versus Vigabatrin in the Prevention of Tuberous Sclerosis Complex Symptoms in Infants

Is NCT04987463 recruiting? Yes, currently enrolling (May 2026). This Phase 2/3 trial studies multiple treatments including Vigabatrin and Rapamycin for tuberous sclerosis complex.

Phase 2/3RecruitingKatarzyna KotulskaNCT04987463Data as of May 2026

Treatment: Vigabatrin · RapamycinThe purpose of the study is to evaluate the efficacy, tolerability, and safety of vigabatrin versus rapamycin as a preventive treatment in infants with Tuberous Sclerosis Complex (TSC).

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Extracted eligibility criteria

Prior therapy

No prior treatment (treatment-naive required)

Cannot have received: antiepileptic treatment

history of antiepileptic treatment

Cannot have received: mTOR inhibitor

history of treatment with mTOR (mammalian Target of Rapamycin) inhibitor

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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