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OncoMatch/Clinical Trials/NCT04974866

Tyrosine Kinase Inhibitors in Metastastic Adenoid Cystic Carcinoma

Is NCT04974866 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies EGFR-TK Inhibitor for carcinoma, adenoid cystic.

Phase 2RecruitingQingdao Central HospitalNCT04974866Data as of May 2026

Treatment: EGFR-TK InhibitorThere is no clinical study on epidermal growth factor receptor tyrosine kinase inhibitors has been systematically conducted in adenoid cystic carcinoma. This is a phase II study EGFR TKIs in adenoid cystic carcinoma to evaluate its efficacy in this disease.

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Extracted eligibility criteria

Performance status

ECOG 0–3(Limited self-care)

Prior therapy

Min 1 prior line

Must have received: chemotherapy

previously treated with chemotherapy or local treatment (e,g transarterial chemoembolization)

Cannot have received: chemotherapy

Exception: last treatment was at least 4 weeks prior to baseline assessment

Prior chemotherapy ... within 4 weeks prior to study entry except palliative radiotherapy to non-target lesions (within 2 weeks prior to study entry)

Cannot have received: radiation therapy

Exception: palliative radiotherapy to non-target lesions (within 2 weeks prior to study entry)

Prior ... radiation therapy ... within 4 weeks prior to study entry except palliative radiotherapy to non-target lesions (within 2 weeks prior to study entry)

Cannot have received: surgery

Prior ... surgery within 4 weeks prior to study entry

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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