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OncoMatch/Clinical Trials/NCT04952480

Dose-escalated Adaptive Radiotherapy of Thoracic Disease for Small Cell Lung Cancer

Is NCT04952480 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Chemotherapy for small cell lung cancer.

Phase 2RecruitingAHS Cancer Control AlbertaNCT04952480Data as of May 2026

Treatment: ChemotherapyThe purpose of this study is to find out what effects of using adaptive radiotherapy to deliver chest radiation has on the ability to control lung cancer and side effects.

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Extracted eligibility criteria

Cancer type

Small Cell Lung Cancer

Performance status

ECOG 0–2(Ambulatory, capable of self-care)

Prior therapy

No prior treatment (treatment-naive required)
Max 0 prior lines

Cannot have received: CNS or thoracic radiotherapy

Previous CNS or thoracic radiotherapy

Cannot have received: chemotherapy

Previous chemotherapy

Cannot have received: thoracic surgery

Prior thoracic surgery

Lab requirements

Kidney function

Kidney disease with irreversibly low creatinine clearance inadequate for IV contrast administration excluded

kidney disease with irreversibly low creatinine clearance inadequate for IV contrast administration (for the purposes of high quality contrast enhanced CT chest and abdomen for follow-up imaging)

Structured fields extracted by AI. May contain errors — verify against the official protocol.

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