OncoMatch

OncoMatch/Clinical Trials/NCT04951622

A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

Is NCT04951622 recruiting? Yes, currently enrolling (May 2026). This Phase 3 trial studies multiple treatments including Nipocalimab and Nipocalimab SC-LIV for myasthenia gravis.

Phase 3RecruitingJanssen Research & Development, LLCNCT04951622Data as of May 2026

Treatment: Nipocalimab · Nipocalimab SC-LIVThe purpose of this study is to evaluate the efficacy and safety of nipocalimab compared to placebo in participants with generalized myasthenia gravis (gMG). The purpose of the subcutaneous substudy is to evaluate how well it works in the body (pharmacodynamic \[PD\]) when given as an injection under the skin (subcutaneous) compared to when given through a vein (intravenous) in participants with gMG.

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Extracted eligibility criteria

Disease stage

Required: Stage MGFA CLASS IIA, MGFA CLASS IIB, MGFA CLASS IIIA, MGFA CLASS IIIB, MGFA CLASS IVA, MGFA CLASS IVB

Excluded: Stage MGFA CLASS I, MGFA CLASS V

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • Neuromuscular Research Center and Clinic · Paradise Valley, Arizona
  • HonorHealth Neurology · Scottsdale, Arizona
  • University of Southern California · Los Angeles, California
  • Stanford University · Palo Alto, California
  • Care Access Research · Pasadena, California

Showing up to 5 US sites. See all sites on ClinicalTrials.gov →

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