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OncoMatch/Clinical Trials/NCT04915508

Extremely Hypofractionated Intensity Modulated Stereotactic Body Radiotherapy for the Treatment of Prostate Cancer With Rising PSA After Radical Prostatectomy

Is NCT04915508 recruiting? Yes, currently enrolling (May 2026). This Phase 2 trial studies Hormone Therapy for prostate adenocarcinoma.

Phase 2RecruitingJonsson Comprehensive Cancer CenterNCT04915508Data as of May 2026

Treatment: Hormone TherapyThis phase II trial investigates the effect of extremely hypofractionated intensity modulated stereotactic body radiotherapy in treating patients with prostate cancer that has rising prostate specific antigen (PSA) after radical prostatectomy. Stereotactic body radiation therapy uses special equipment to position a patient and deliver radiation to tumors with high precision. This method may kill tumor cells with fewer doses over a shorter period and cause less damage to normal tissue. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects.

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Extracted eligibility criteria

Cancer type

Prostate Cancer

Disease stage

Required: Stage IIIB, IIIC, IV, IVA, IVB (AJCC v8)

Stage IIIB Prostate Cancer AJCC v8; Stage IIIC Prostate Cancer AJCC v8; Stage IV Prostate Cancer AJCC v8; Stage IVA Prostate Cancer AJCC v8; Stage IVB Prostate Cancer AJCC v8

Prior therapy

Must have received: radical prostatectomy — definitive intent

treated with radical prostatectomy with definitive intent

Cannot have received: pelvic radiotherapy

Prior pelvic radiotherapy

Structured fields extracted by AI. May contain errors — verify against the official protocol.

US trial sites

  • UCLA / Jonsson Comprehensive Cancer Center · Los Angeles, California

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